هاي فارم
عودة
الهدف والقيم
تسهيلات هاي فارم
الوحدة التجارية
اللوجيستيات والمشتريات
المسؤولية الاجتماعية للشركات
نحن نقدم
نحن نركز على
البحث والتطوير
السيرة
الأعمال الإلكترونية
Steronate is a synthetic progestin that is used for treating menstrual irregularities as well as postponing menstruation if needed.
Norethisterone is a progestin that binds to the progesterone receptors on cells giving the effect of normal progesterone as well as exerting a negative feedback effect on the hypothalamus and pituitary glands suppressing the release of the Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) which in turn suppresses the development of the follicles, ovulation, and development of corpus luteum.
Norethisterone does not bind to other steroid as androgenic receptors and glucocorticoid receptors due to its low affinity which makes it with the least off-target activity.
– A Transformative effect: Flexible dosing for insufficient luteal phase indications
– 80-150mg for 8-10 days achieve complete endometrium transformation, up to the condition which it’s normally in at the end of the luteal phase
– Styptic effect: Steronate has a local effect on endometrium leading to the cessation of bleeding
– Ovulation-Inhibitory effect: inhibits the secretion of gonadotropins in the anterior lobe of the pituitary that prevents follicular maturation & ovulation – with the least androgenic effect.
– Abnormal Uterine Bleeding: stabilizes the endometrium & inhibits synthesis of prostaglandin F-2 alpha, leads to the arrest of uterine bleeding with 1 to 3 days, and assisting in the differential diagnosis of uterine bleeding. (It’s better in treating AUB than Dydrogesterone)
– Steronate-Progesterone challenge test: Steronate has 50% more progesterone receptor affinity than progesterone itself.
– Affordable and economic
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