Anti-inflammatories

Allergic inflammation happened due to a complex interaction between several inflammatory cells, including mast cells, basophils, lymphocytes, dendritic cells, eosinophils, and sometimes neutrophils. These cells produce multiple inflammatory mediators, including lipids, purines, cytokines, chemokine, and reactive oxygen species.

So, Hi Pharm was so keen to provide the Egyptian market with high-quality products to treat health problems related to allergies.

Fexofenadine

Fexofenadine is a metabolite of terfenadine. Labeled third-generation because it is an active metabolite of second-generation drug. Blocks the effects of histamine.

What makes Fexofenadine of Hi Pharm your upper hand treatment for inflammation reactions?

Fexofenadine is FDA approved for the treatment of the symptoms of allergic rhinitis and chronic idiopathic urticaria.

Fexofenadine, as an H1-receptor blocker is useful in treating and preventing allergic reactions; caused by antigens acting on immunoglobulin E antibodies. Controlling the symptoms of allergic rhinitis, and urticaria because histamine is the principal mediator released by mast cells.
Effectively ameliorates the symptoms of seasonal allergic rhinitis (SAR) including rhinorrhea, sneezing, pruritus, and itchy, watery eyes, and as a single entity has demonstrated a favorable effect on nasal congestion.

fexofenadine is more effective than loratadine at relieving the individual symptoms of nasal congestion, itchy, watery, and red eyes to have comparable efficacy to cetirizine.
Fexofenadine is both nonsedating and produces no adverse cardiac effects even at supratherapeutic doses and has demonstrated various antiallergic activities both in vivo and in vitro.
Cumulatively, these benefits distinguish fexofenadine from other antihistamines, making it a unique therapeutic option for treating several allergy-mediated respiratory or dermatologic diseases.
Fexofenadine has an excellent safety profile, with no sedating effect, and is not associated with cardiac adverse events.

Montelukast

That featured agent in Hi Pharm’s anti-inflammatory portfolio. your drug of choice in the treatment of the different allergic problems as Urticaria, Angioedema, and helps in Atopic Dermatitis.

Control Asthma with Montelukast:

You can confidently use Montelukast in the prophylaxis, and the treatment of chronic asthma, including prevention of day- and night-time symptoms.
Montelukast is effective in the prevention of exercise-induced bronchoconstriction (EIB).
Montelukast is effective alone or in a combination with other agents used in the maintenance treatment of chronic asthma.
Montelukast can be an additional treatment option following initial management with an “as needed” short-acting beta-agonist (SABA), an inhaled corticosteroid, or inhaled corticosteroid together with a long-acting beta-agonist.

Montelukasts’ safety margin:

Montelukast is indicated for the relief of symptoms of seasonal allergic rhinitis (SAR) Perennial allergic rhinitis(PAR) in patients 15 years old or older.
Montelukast is well tolerated with a safety profile that is similar in adult and pediatric populations.

Defeat the inflammation directly with Hi Pham cox2 selective inhibitor:

Celecoxib

This selective action of Celecoxib provides the benefits of reducing inflammation without the increased risk of stomach irritation, ulceration, and bleeding.
A potent anti-inflammatory, analgesic, and anti-pyretic.
Rapid action and long.

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