Cardiovascular Agents

The cardiovascular system refers to the heart, blood vessels, and blood. Blood contains oxygen and other nutrients which your body needs to survive. The body takes these essential nutrients from the blood.

So, If a problem appears that affects the performance of this vital system, the whole body is affected
Therefore, we at Hi Pharm are fortified to provide a complete portfolio that includes treatment for the most common health problems that the cardiovascular system may be exposed to.

Hi Pharm is proudly introducing the unique ACE inhibitor molecule Lisinopril.

Why do you need an ACE inhibitor Lisinopril to be prescribed?

For Hypertension:

The goal of antihypertensive therapy is not only to lower blood pressure but, more importantly; to alter the risk of end-organ damage and mortality. Lisinopril can treat hypertension with coexistent conditions such as congestive heart failure and diabetic nephropathy.

By reducing angiotensin II formation leads to arterial and venous dilation, which reduces arterial and venous pressures. By reducing the effects of angiotensin II on the kidney, ACE inhibitors cause natriuresis and diuresis, which decrease blood volume and cardiac output, thereby lowering arterial pressure.

Heart Failure with Hypertension

Lisinopril/ lisinopril-thiazide can decrease vascular resistance (afterload) and venous tone (preload), resulting in increased cardiac output. Lisinopril also blunts the usual angiotensin II-mediated increase in epinephrine and aldosterone have seen in HF.
Reduce afterload, which enhances ventricular stroke volume and improves ejection fraction.
Reduced preload, which decreases pulmonary and systemic congestion and edema.
Reduced sympathetic activation, which is deleterious in heart failure.
Improving the oxygen supply/demand ratio primarily by decreasing demand through the reductions in afterload and preload.
Prevents remodeling, Unlike ARBs
Following myocardial infarction because they help to reduce deleterious remodeling that occurs post-infarction.
Mortality Reduction after Acute MI, Lisinopril is a vital team player in improving the survival rate in hemodynamically stable patients with acute MI.

You need Lisinopril-thiazides in:

In Heart failure with Hypertension.
In Hypercalciuria with Hypertension.
In Diabetes insipidus with Hypertension.
In Hyperuricemia with Hypertension.
In Volume depletion with Hypertension.
In Hypercalcemia with Hypertension.

Pulmonary hypertension

Hi Pharm has a model portfolio for pulmonary hypertension treatment by providing

Lisinopril/ Lisinopril-thiazide, with its ability to reduce high pressure and improve cardiac muscle remodeling with its mode of action.
Sildenafil,
- Sildenafil improves functional capacity, hemodynamic parameters, its benefits start as early as 2 weeks.
- The effects are dose-related.
- Being very effective, widely available, relatively inexpensive, and very easy to use, and very well tolerated without any major side effect
- Sildenafil may qualify as a first-line medication for these patients.

Hypotension

What do you need to defeat hypotension?

You need an agent of rapid onset.
can act on different causes of hypotension as:
Perioperative hypotension
Levodopa (Sinemet) related Hypotension
Secondary Hypotension, due to; Hypotensive circulatory disorder. circulatory failure and collapse.
Hypotension that may occur in myocardial infarction, accidents, during pregnancy, convalescence, chronic disease, and tumor cachexia.

Simply you need our unique Etilefrine to be your upper hand treatment of hypotension causes.

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